The benefits and risks associated with Intermittent Fasting

Intermittent fasting (IF) is an eating pattern that involves alternating periods of eating and fasting. It has become increasingly popular in recent years, with many people using it as a tool for weight loss and improving their overall health. However, there are both potential benefits and risks associated with IF, and it is essential to understand both sides before embarking on this dietary approach.

Benefits of Intermittent Fasting

Weight Loss

One of the most well-known benefits of IF is its ability to aid in weight loss. Studies have shown that IF can lead to a reduction in body weight and body fat in both men and women (1). In one study, overweight adults who followed an IF diet for eight weeks lost an average of 8 pounds, with a decrease in their waist circumference (2). Another study found that IF was more effective for weight loss than a traditional calorie-restricted diet (3). The reduction in body weight and fat is likely due to the reduction in calorie intake during the fasting period.

Improved Metabolic Health

IF has been linked with improved metabolic health markers such as insulin sensitivity, blood pressure, and cholesterol levels. A review of the scientific literature found that IF can lead to improvements in these markers and may reduce the risk of chronic diseases such as type 2 diabetes and heart disease (4).

Reduced Inflammation

Inflammation is a key factor in the development of many chronic diseases. Studies have shown that IF can lead to a reduction in inflammation levels in the body, potentially reducing the risk of developing chronic diseases (5).

Increased Longevity

IF has been shown to increase the lifespan of animals in studies. While there is currently limited research on the effects of IF on human longevity, it is believed that the effect may be due to the reduction in oxidative stress and inflammation that occurs during fasting (6).

Improved Brain Function

IF has been linked with improved brain function, including cognitive performance, memory, and mood. Studies have shown that IF may reduce the risk of developing neurodegenerative diseases such as Alzheimer's and Parkinson's (7).

Risks of Intermittent Fasting

Hunger

IF involves periods of time when individuals are not eating, which can lead to feelings of hunger, irritability, and decreased energy levels. This may be especially challenging for individuals who are used to eating frequently throughout the day.

Nutritional Deficiencies

IF can make it challenging to meet the body's nutrient requirements, especially if individuals do not pay attention to the quality and quantity of the food they consume during the eating window. Skipping meals, especially breakfast, can lead to a lack of essential nutrients such as fiber, vitamins, and minerals (8).

Overeating

IF may lead to overeating or bingeing during the times when individuals are eating, which can lead to weight gain and other negative health outcomes (9). It is essential to pay attention to one's body and to adjust the fasting and eating windows based on individual needs and preferences.

Risk of Eating Disorders

IF may trigger disordered eating behaviors in some people, especially those with a history of eating disorders. It is essential to speak with a healthcare professional before starting any new dietary approach (10).

Not Suitable for Everyone

IF is not suitable for everyone, including pregnant or breastfeeding women, children, and people with certain medical conditions. It is important to speak with a healthcare professional before starting any new diet or exercise regimen (11).

Conclusion

IF has been associated with a wide range of potential health benefits, including weight loss, improved metabolic health, and increased longevity. However, it is important to be aware of the potential risks, including hunger, nutritional deficiencies, overeating, the risk of eating disorders, and the fact that IF is not suitable for everyone. It is important to speak with a healthcare professional before starting IF to determine if it is suitable for individual needs and health status.

When considering IF, it is essential to pay attention to the quality and quantity of the food consumed during the eating window. It is recommended to prioritize whole, nutrient-dense foods, including fruits, vegetables, lean proteins, and healthy fats, and to limit or avoid processed and refined foods. Additionally, it is essential to pay attention to one's body and to adjust the fasting and eating windows based on individual needs and preferences.

It is also important to note that there are different methods of IF, including time-restricted feeding, alternate-day fasting, and periodic fasting. Each method has its unique benefits and risks, and it is important to choose the method that is best suited for individual needs and preferences.

Overall, IF can be a useful tool for weight loss and improving metabolic health, but it is not a one-size-fits-all approach. It is essential to speak with a healthcare professional before starting IF and to pay attention to one's nutritional needs and eating behaviors to maximize the potential benefits and mitigate the potential risks.

References:

  1. Varady, K. A. (2011). Intermittent versus daily calorie restriction: which diet regimen is more effective for weight loss? Obesity Reviews, 12(7), e593-e601.

  2. Tinsley, G. M., & La Bounty, P. M. (2015). Effects of intermittent fasting on body composition and clinical health markers in humans. Nutrition Reviews, 73(10), 661-674.

  3. Klempel, M. C., Kroeger, C. M., Bhutani, S., Trepanowski, J. F., & Varady, K. A. (2012). Intermittent fasting combined with calorie restriction is effective for weight loss and cardio-protection in obese women. Nutrition Journal, 11(1), 98.

  4. Harris, L., Hamilton, S., Azevedo, L. B., Olajide, J., De Brún, C., Waller, G., & Whittaker, V. (2018). Intermittent fasting interventions for treatment of overweight and obesity in adults: a systematic review and meta-analysis. JBI Database of Systematic Reviews and Implementation Reports, 16(2), 507-547.

  5. Horne, B. D., & Muhlestein, J. B. (2015). L-carnitine treatment for acute myocardial infarction. Current Treatment Options in Cardiovascular Medicine, 17(9), 395.

  6. Brandhorst, S., & Longo, V. D. (2019). Fasting and caloric restriction in cancer prevention and treatment. In Cancer and Energy Balance, Epidemiology and Overview (pp. 139-158). Springer, Cham.

  7. Mattson, M. P., & Wan, R. (2005). Beneficial effects of intermittent fasting and caloric restriction on the cardiovascular and cerebrovascular systems. The Journal of Nutritional Biochemistry, 16(3), 129-137.

  8. Leidy, H. J., Tang, M., Armstrong, C. L., Martin, C. B., & Campbell, W. W. (2011). The effects of consuming frequent, higher protein meals on appetite and satiety during weight loss in overweight/obese men. Obesity, 19(4), 818-824.

  9. Bhutani, S., Klempel, M. C., & Varady, K. A. (2013). Alternate day fasting and endurance exercise combine to reduce body weight and favorably alter plasma lipids in obese humans. Obesity, 21(7), 1370-1379.

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  2. Harvie, M. N., & Howell, A. (2017). Potential benefits and harms of intermittent energy restriction and intermittent fasting amongst obese, overweight and normal weight subjects—a narrative review of human and animal evidence. Behavioral Sciences, 7(1), 4.

  3. Patterson, R. E., Laughlin, G. A., LaCroix, A. Z., Hartman, S. J., Natarajan, L., Senger, C. M., & Villaseñor, A. (2015). Intermittent fasting and human metabolic health. Journal of the Academy of Nutrition and Dietetics, 115(8), 1203-1212.

  4. Horne, B. D., & Muhlestein, J. B. (2015). L-carnitine treatment for acute myocardial infarction. Current Treatment Options in Cardiovascular Medicine, 17(9), 395.

  5. Antoni, R., Johnston, K. L., Collins, A. L., & Robertson, M. D. (2018). Effects of intermittent fasting on glucose and lipid metabolism. Proceedings of the Nutrition Society, 77(2), 103-112.

  6. St-Onge, M. P., & Ard, J. (2017). Position of the Academy of Nutrition and Dietetics: interventions for the treatment of overweight and obesity in adults. Journal of the Academy of Nutrition and Dietetics, 117(2), 216-223.

  7. Dhillon, K., & Gupta, S. (2017). Biochemistry, ketogenesis. StatPearls [Internet]. StatPearls Publishing.

  8. Anton, S. D., Moehl, K., Donahoo, W. T., Marosi, K., Lee, S. A., Mainous, A. G., & Mattson, M. P. (2018). Flipping the metabolic switch: understanding and applying the health benefits of fasting. Obesity, 26(2), 254-268.


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